PowerEdge R650 Supported Drives

Internal drive bay and hot-plug backplane:
Up to 8 or 10 x 2.5” HDD: SAS, SATA, Near-line SAS SSD: SAS, SATA
Up to 4 x 3.5” HDD: SAS, SATA, Near-line SAS SSD: SAS, SATA 

Chassis with up to 10 x 2.5" drives with up to 12 NVMe also available.

Datasheet: R650 spec sheet